Advanced Synthetic Methodologies

Explore breakthrough research articles, reaction mechanisms, and innovative strategies in organic synthesis.

Research Articles

Nature's Blueprint: The Radical New Way to Build Healing Molecules

Discover how radical chemistry is revolutionizing the synthesis of furanocoumarins, unlocking new possibilities for drug discovery from ancient plants.

Jackson Simmons
Aug 20, 2025

The Single-Electron Revolution: How Catalysis Is Being Rewritten One Radical at a Time

Exploring the paradigm shift in catalysis from two-electron reactions to single-electron radical processes, enabled by cutting-edge technologies and quantum principles.

Emily Perry
Aug 12, 2025

The Radical Makeover: How Ruthenium Gave New Life to a Classic Reaction

Discover how ruthenium catalysts transformed the classic Barton-McCombie reaction through a pseudoreversible radical pathway, enabling efficient O-to-S alkyl migrations.

Charles Brooks
Aug 10, 2025

The Silent Revolution: How Radical Chemistry Rewrote Aromatic Substitution Rules

Discover how the SRN1 reaction challenged century-old chemistry dogma, enabling radical-based aromatic substitutions on previously unreactive compounds.

Easton Henderson
Aug 08, 2025

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